OpenSMOG is a Python library for performing molecular dynamics simulations using Structure-Based Models . OpenSMOG uses the OpenMM Python API that supports a wide variety of potential forms, which includes the commonly employed C-alpha  and All-Atom  models.
The input files are generated using the SMOG2 software package with the flag
-OpenSMOG. Details on SMOG2 usage can be found in the SMOG2 User Manual.
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